Living Well: Why the Cold and Flu Seasons Are Bringing Down the Covid-19 Threshold in the Rhine: A Discovery from a Scientific Detective Hunt
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A chill is in the air, and you all know what that means — it’s time for cold and flu season, when it seems everyone you know is suddenly sneezing, sniffling or worse. The first blast of winter weather is almost as if the cold and flu germs are going to show up.
Yet germs are present year-round — just think back to your last summer cold. People get more colds, flu, and now Covid-19 when it’s chilly outside.
“This is the first time that we have a biologic, molecular explanation regarding one factor of our innate immune response that appears to be limited by colder temperatures,” said rhinologist Dr. Zara Patel, a professor of otolaryngology and head and neck surgery at Stanford University School of Medicine in California. She was not involved in the new study.
When exposed to cold air the temperature in your nose can go up or down by as much as 9 degrees. It knocks out the immune advantages that the nose has.
Although it is using human tissue in the lab to study this Immune response, it is not a study inside someone’s actual nose. Not always the findings of in vitro studies are confirmed in the real world.
To understand why it happens, a team of scientists and their author went on a scientific detective hunt.
The nasal mucus of a hornet produces more cells than original cells, so that the immune system can fight off viruses, bacteria and Covid-19
A respiratory virus or bacteria invades the nose, the main point of entry into the body. Immediately, the front of the nose detects the germ, well before the back of the nose is aware of the intruder, the team discovered.
What happens if you kick a hornet’s nest? If you kick a hornet, all the others in the nest will fly out to attack before an animal can get into the nest itself, he said. “That’s the way the body mops up these inhaled viruses so they can never get into the cell in the first place.”
Those “Mini Me’s” are then expelled by the cells into nasal mucus (yes, snot), where they stop invading germs before they can get to their destinations and multiply.
“This is one of, if not the only part of the immune system that leaves your body to go fight the bacteria and viruses before they actually get into your body,” Bleier said.
When under attack, the nose increases production of extracellular vesicles by 160%, the study found. There were additional differences: EV’s had many more receptors on their surface than original cells, thus boosting the virus-stopping ability of the billions of extracellular vesicles in the nose.
If you reduce the amount ofRNA inside each vesicle, it will result in a reduction in the number ofreceptors, making them less sticky.
What does that do to your ability to fight off colds, flu and Covid-19? It cuts your immune system’s ability to fight off respiratory infections by half, Bleier said.
“Not only do masks prrhinologist Dr. Benjamin Bleierotect you from the direct inhalation of viruses, but it’s also like wearing a sweater on your nose,” he said.
In the future, Bleier expects to see the development of topical nasal medications that build upon this scientific revelation. The pharmaceuticals will fool the nose into thinking there’s a sick person in it.
How many vesicles were secreted by a heating effect on the neutron-rich cells of Lambda Amiji?
To figure out how many vesicles were being secreted in response to this stimulation, the scientists collected the media that the cells were immersed in, then used a centrifuge to extract the vesicles. When the cells were attacked by thisimic they increased their excretions. The Warming Effect creates a flood-like mechanism of disarming the pathogen, according to Amiji.